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For example, the analgesic morphine reduces pain but can affect other aspects of behaviour in pain-free animals, for example, excitement, increased activity or sedation, which can hamper traditional behavioural assessment of its action on pain. Good agreement has been found between these [23] in relation to three models of pain intra plantar carrageenan , intraplantar complete Freund's adjuvant and plantar incision. There is no difference in GS scores between mice handled using a tube compared with mice picked up by the tail, indicating these handling techniques are not confounding factors in GS assessment. For this reason, behavioural changes in these species are mainly observed with acute pain hours but are less pronounced in longer-lasting pain days.


scale facial grimace
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scale facial grimace
scale facial grimace
scale facial grimace
scale facial grimace
scale facial grimace
scale facial grimace
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scale facial grimace
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